Thursday Night Football: Buffalo Bills vs Houston Texans Preview + Odds
The Bills hit the road to face the Texans and the league’s top-ranked defense. With Josh Allen coming off a 6-TD game and Houston missing C.J. Stroud, this primetime matchup sets up a tough test for both sides.
1. Bills Look to Stay Hot After Josh Allen’s 6-TD Game
The Buffalo Bills are 2–2 on the road this season and haven’t looked nearly as dominant away from home. They’ll face a major test against a Texans defense in week 12 of the NFL that currently ranks No. 1 in total defense, making life difficult for opposing quarterbacks all year. Josh Allen is coming off a monster 6-TD performance against the Buccaneers, but Houston’s defense will challenge him both through the air and on the ground.
On the other side, the Texans will once again be without C.J. Stroud, who remains in concussion protocol since Week 10. Davis Mills steps in and has held his own with wins over the Jaguars and Titans, but he’ll face heavy pressure from a tough Bills defense under the primetime lights. This matchup has all the ingredients for a physical, defense-driven showdown.
Check out the full game info and betting odds below.
Bet responsively.
Game info
How to watch: Prime Video
Kickoff: 7:15 p.m. EST
Where: NRG Stadium
| Week 12 | Spread | Moneyline | Total |
|---|---|---|---|
| BUF Bills | -6 (-108) | -290 | O 43.5 -105 |
| HOU Texans | +6 (-112) | +235 | U 43.5 -112 |
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